Bora Pharmaceuticals looks at how to synchronise and control API delivery, and why extrusion-spheronization offers pharmaceutical companies a robust technique to manufacture today’s most complex therapeutics.
Strategy
Manufacturing spherical oral solid dose pellets via extrusion-spheronization is not new. What is new is that in the right hands, with the right capabilities, this well-understood process stands ready to help lead the development and manufacturing of both today and tomorrow’s complex oral solid dose drug products.
Extrusion-spheronization is an efficient, flexible and fast process for forming uniform pharmaceutical particles. The shape offers great utility to both drug developers and manufacturers. Offering a low surface area to volume ratio, spheronized active pharmaceutical ingredients (APIs) offer a number of distinct advantages that improve the overall manufacturability of complex dose forms.