With a trend moving towards more use of single-use bioprocess bags to transport biopharmaceutical solutions Dujuan Lu, PhD (technical client manager/global lead, SGS Life Science Services) and Kate Comstock (senior marketing specialist, Thermo Fisher Scientific) assess whether or not contaminants leach out from these bags, potentially creating a risk to patient safety.
contamination
Single-use bioprocess bags are increasingly being used for the preparation, storage and transport of biopharmaceutical solutions, intermediates and final bulk products. These bags are made from plastic materials, and there is the risk that contaminants, additives and degradants may leach out into the cell culture media and remain inside final drug products.