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Leveraging Modified Release Formulations for Targeted Therapeutic Delivery

In this article, Dr. Asma Patel, Vice President of Integrated Development Services at Quotient Sciences, explores the benefits of MR formulations, highlighting the importance of an effective strategy for MR development.

Leveraging Modified Release Formulations for Targeted Therapeutic Delivery
Published: | 4 min read

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Oral solid dosage (OSD) forms are commonly used to administer small molecule drugs to patients, facilitating ease of administration to result in rapid delivery and benefit. This modality is most commonly used for immediate release (IR) formulations, where the drug instantly dissolves and is released. Despite the advantages of experiencing an immediate effect, this instantaneous release can lead to a short duration of action, requiring frequent dosage and resulting in release peaks and troughs in the bloodstream, which can lead to side effects or reduce therapeutic efficacy.

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