In this study, organic solutions and aqueous dispersions of ethylcellulose (EC) were used to prepare a prolonged drug release dosage form consisting of a single dose of drug subdivided into many small units.
As a drug model, a non-steroidal anti-inflammatory drug was chosen, and as core substrate, the pellets prepared by extrusion-spheronisation technology were used. The coating equipment used was a modified GS pilot pan supplied with two perforated immersion swords.
Introduction