Lakiya Wimbish, Lonza, discusses the benefits of recombinant Factor C based endotoxin testing
Endotoxins are lipopolysaccharides found in the outer membrane of Gram-negative bacteria. These pyrogenic components can elicit an immune response if administered via the blood stream through contaminated parenteral drugs or other medical devices. Hence, bacterial endotoxin testing (BET) needs be carried out for all such products in order to prevent any adverse effects.